Impact of COVID-19 in patients hospitalized with stress cardiomyopathy: A nationwide analysis

Authors

Adrija Hajra, Department of Internal Medicine, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, NY, USA.
Aaqib Malik, Department of Cardiology, Westchester Medical Center, New York Medical College, Valhalla, NY, USA.
Dhrubajyoti Bandyopadhyay, Department of Cardiology, Westchester Medical Center, New York Medical College, Valhalla, NY, USA.
Akshay Goel, Department of Cardiology, Westchester Medical Center, New York Medical College, Valhalla, NY, USA.
Ameesh Isath, Department of Cardiology, Westchester Medical Center, New York Medical College, Valhalla, NY, USA.
Rahul Gupta, Department of Cardiology, Lehigh Valley Heart Institute, Lehigh Valley Health Network, Allentown, PA, USA.
Suraj Krishnan, Department of Internal Medicine, Jacobi Medical Center/Albert Einstein College of Medicine, Bronx, NY, USA.
Devesh Rai, Rochester Regional HealthFollow
Chayakrit Krittanawong, Department of Cardiology, NYU Langone Health, New York, USA.
Salim S. Virani, Michael E. DeBakey Veterans Affairs Medical Center, Section of Cardiovascular Research, Baylor College of Medicine, Houston, TX, USA.
Gregg C. Fonarow, Ahmanson-UCLA Cardiomyopathy Center, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA., USA.
Carl J. Lavie, John Ochsner Heart and Vascular Institute, Ochsner Clinical School, The University of Queensland School of Medicine, New Orleans, LA, USA.

Department

Cardiology

Document Type

Article

Publication Title

Progress in Cardiovascular Diseases

Abstract

Stress cardiomyopathy was noted to occur at a higher incidence during coronavirus disease of 2019 (COVID-19) pandemic. This database analysis has been done to compare the in-hospital outcomes in patients with stress cardiomyopathy and concurrent COVID-19 infection with those without COVID-19 infection. The National Inpatient Sample database for the year 2020 was queried to identify all admissions diagnosed with stress cardiomyopathy. These patients were then stratified based on whether they had concomitant COVID-19 infection or not. A 1:1 propensity score matching was performed. Multivariate logistic regression analysis was done to identify predictors of mortality. We identified 41,290 hospitalizations for stress cardiomyopathy, including 1665 patients with concurrent diagnosis of COVID-19. The female preponderance was significantly lower in patients with stress cardiomyopathy and COVID-19. Patients with concomitant COVID-19 were more likely to be African American, diabetic and have chronic kidney disease. After propensity matching, the incidence of complications, including acute kidney injury (AKI), AKI requiring dialysis, coagulopathy, sepsis, cardiogenic shock, cases with prolonged intubation of > 24 h, requirement of vasopressor and inpatient mortality, were noted to be significantly higher in patients with COVID-19. Concomitant COVID-19 infection was independently associated with worse outcomes and increased mortality in patients hospitalized with stress cardiomyopathy.

First Page

25

Last Page

30

DOI

10.1016/j.pcad.2022.12.002

Volume

76

Issue

1

Publication Date

1-2023

PubMed ID

36528166

Recommended Citation

Hajra, A., Malik, A., Bandyopadhyay, D., Goel, A., Isath, A., Gupta, R., Krishnan, S., Rai, D., Krittanawong, C., Virani, S. S., Fonarow, G. C., & Lavie, C. J. (2023). Impact of COVID-19 in patients hospitalized with stress cardiomyopathy: A nationwide analysis. Progress in Cardiovascular Diseases, 76 (1), 25-30. https://doi.org/10.1016/j.pcad.2022.12.002