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Published quarterly by Rochester Regional Health, Advances in Clinical Medical Research & Healthcare Delivery (ACMRHD) is a diamond open access journal that publishes original research, guidelines, case reports and series, narrative reviews, systematic reviews and commentaries on a broad range of medical topics. We accept submissions in all article categories and we do not charge article processing fees. For more details see our information for authors. If you are interested in joining our team of volunteer peer reviewers of submissions to the journal, please contact us.

Current Issue: Volume 6, Issue 2 (2026)

Case Reports

A Case of Reversible Acute Kidney Injury and Life-Threatening Gastrointestinal Bleed with Colitis in a Patient Receiving Tucatinib for HER2-Positive Breast Cancer
Geetha Keshav, Shanzae Naeem, and Jalila Jafri

Invasive Non-typhoidal Salmonella Enterocolitis and Bacteraemia with Negative initial stool culture following consumption of ``Ceviche''- A Case Report
Maria Vasnaik, Nimrat Kaur Sandhu, and Justin Nistico

Intravenous Phenytoin-Induced Purple Glove Syndrome with Transient Hyperpigmentation: A Rare Adverse Drug Reaction in an Elderly Patient
Aarthi MA and REVANTH R

Checkpoint Inhibitor–Associated Autoimmune Diabetes Following PD-1 Blockade: Severe Diabetic Ketoacidosis After Pembrolizumab
Divya Samat, Osadebamwen Osaghae, Shivam Singh, Mohammad Abu Tineh, and Anthony Donato

Appendiceal Neuroendocrine Tumor: A Case Report
Daniel Zipfel, Thomas Russo, and Mathew Devine

Ultrasound-Guided Epidural Caudal Block for Lumbar Spinal Stenosis in a Patient with Severe Scoliosis: A Case Report
Theresia Chandra Tania Novy, Daniel Hadimartana, and Maria Jessica Yaputri

Toxoplasmosis-Associated Immune Reconstitution Inflammatory Syndrome in a Patient with Newly Diagnosed HIV/AIDS
Shivam Singh, Divya Samat MD, Viraj Shah, Kelly Brenan-Rothschild, and Anthony Donato

Spontaneous Isolated Celiac Artery Dissection - A Case Report
Marina Takawy, Yousef Waly, Mohanad Shehadeh, Mostafa Najim, and Richard Alweis

Original Study

Nationwide Analysis of Catheter-Directed Thrombolysis Versus Anticoagulation in Sub-Massive Pulmonary Embolism
Ayushma Acharya, Swarup Sharma Rijal, and Anthony Donato

Reviews

Vitamin D Deficiency and Risk of Cognitive Decline and Dementia: Implications and Prevention Strategies
auda Fares

Addressing DOscrimination: Examining Bias Against Osteopathic Physicians
Sophia M. Valerino

Personal Narratives

Solutions to Dismantling Osteopathic Bias in American Medicine
Mathew Devine and Richard Terry

Beyond the Algorithm: Empowering Clinicians and Researchers to Thrive in the Age of AI
Milan Sheth and Justin S. Brathwaite