Penicillin Allergy Delabeling: A Multidisciplinary Opportunity

Department

Allergy and Immunology

Document Type

Article

Publication Title

Journal of Allergy and Clinical Immunology: In Practice

Abstract

The penicillin allergy label has been consistently linked with deleterious effects that span the health care spectrum, including suboptimal clinical outcomes, the emergence of bacterial resistance, and increased health care expenditures. These risks have recently motivated professional organizations and public health institutes to advocate for the implementation of penicillin allergy delabeling initiatives; however, the burden of delabeling millions of patients is too expansive for any one discipline to bear alone. This review presents the unique perspectives and roles of various stakeholder groups involved in penicillin allergy diagnosis, assessment, and delabeling; we emphasize opportunities, barriers, and promising areas of innovation. We summarize penicillin allergy methods and tools that have proven successful in delabeling efforts. A multidisciplinary approach to delabeling patients with reported penicillin allergy, bolstered by evidence-based clinical practices, is recommended to reduce the risks that associate with the penicillin allergy label.

First Page

2858

Last Page

2868.e16

DOI

10.1016/j.jaip.2020.04.059

Volume

8

Issue

9

Publication Date

10-1-2020

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