Acute on Chronic Immune Thrombocytopenia as a Cause of Thrombocytopenia in Sepsis
Department
Internal Medicine
Document Type
Article
Publication Title
Cureus
Abstract
Immune thrombocytopenia (ITP) is a diagnosis of exclusion and can be challenging at times to make the diagnosis. We herein present a case of a 73-year-old male with a history of chronic ITP, who presented to the hospital with sepsis and developed thrombocytopenia. His thrombocytopenia did not improve with resolution of sepsis but improved with ITP treatment including immunoglobulins and steroids. Platelet-associated IgG antibody levels are inversely proportional to platelet counts. The antibody levels are increased in sepsis. We would like to highlight that other causes of thrombocytopenia should also be considered in sepsis.
First Page
e8168
DOI
10.7759/cureus.8168
Volume
12
Issue
5
Publication Date
5-17-2020
PubMed ID
32550083
Recommended Citation
Kudaravalli, P., Pendela, V. S., & Gambhir, H. S. (2020). Acute on Chronic Immune Thrombocytopenia as a Cause of Thrombocytopenia in Sepsis. Cureus, 12 (5), e8168. https://doi.org/10.7759/cureus.8168