Anaplastic Large Cell Lymphoma Presenting as Haemophagocytic Lymphohistiocytosis with Underlying Coxiella burnetii and Bartonella henselae Seropositivity
Department
Internal Medicine
Document Type
Article
Publication Title
European Journal of Case Reports in Internal Medicine
Abstract
A 44-year-old woman with no significant medical history presented with a 3-week history of high-grade fevers, fatigue and shortness of breath. Laboratory investigation was significant for lymphopenia and thrombocytopenia which progressively worsened during her hospital stay, along with new-onset anaemia, and elevated ferritin, transaminase and triglycerides. A computerized tomography (CT) scan of the abdomen revealed retroperitoneal lymphadenopathy. A bone marrow biopsy confirmed the diagnosis of haemophagocytic lymphohistiocytosis (HLH). Extensive infectious work-up revealed high IgG titres for
LEARNING POINTS: Haemophagocytic lymphohistiocytosis (HLH) is an important differential diagnosis to consider for fever of unknown origin in adults, especially in the setting of pancytopenia and hyperferritinaemia.Q fever resulting from
First Page
001850
Last Page
001850
DOI
10.12890/2020_001850
Volume
7
Issue
11
Publication Date
8-6-2020
PubMed ID
33194860
Recommended Citation
Ammad Ud Din, M., Hussain, S., Said, B., & Zafar, A. (2020). Anaplastic Large Cell Lymphoma Presenting as Haemophagocytic Lymphohistiocytosis with Underlying Coxiella burnetii and Bartonella henselae Seropositivity. European Journal of Case Reports in Internal Medicine, 7 (11), 001850-001850. https://doi.org/10.12890/2020_001850