Graded Administration of Second Dose of Moderna and Pfizer-BioNTech COVID-19 mRNA Vaccines in Patients With Hypersensitivity to First Dose

Authors

Linh-An C. Tuong, Rochester Regional HealthFollow
Peter Capucilli, Rochester Regional HealthFollow
Mary Staicu, Rochester Regional HealthFollow
Allison Ramsey, Rochester Regional HealthFollow
Edward E. Walsh, Rochester Regional HealthFollow
S. Shahzad Mustafa, Rochester Regional HealthFollow

Department

Allergy and Immunology

Document Type

Article

Publication Title

Open Forum Infectious Diseases

Abstract

Two mRNA coronavirus disease 2019 (COVID-19) vaccines, Moderna and Pfizer-BioNTech, require 2 doses for maximum efficacy. This case series reports the safety and immunogenicity of a graded administration of the second dose of the Moderna and Pfizer-BioNTech COVID-19 vaccines in patients with immediate hypersensitivity reactions to the first dose.

DOI

10.1093/ofid/ofab507

Volume

8

Issue

12

Publication Date

12-1-2021

PubMed ID

34873577

Recommended Citation

Tuong, L. C., Capucilli, P., Staicu, M., Ramsey, A., Walsh, E. E., & Mustafa, S. S. (2021). Graded Administration of Second Dose of Moderna and Pfizer-BioNTech COVID-19 mRNA Vaccines in Patients With Hypersensitivity to First Dose. Open Forum Infectious Diseases, 8 (12) https://doi.org/10.1093/ofid/ofab507