Acquired Hemophilia A in Peripartum Period: Diagnostic and Therapeutic Dilemma

Department

Oncology and Hematology

Document Type

Article

Publication Title

Cureus

Abstract

Acquired hemophilia A (AHA) is a bleeding diathesis caused by auto-antibody generation against factor VIII, an essential component of the coagulation cascade. Although having many etiologies, pregnancy is also one of the conditions associated with AHA. It mostly presents as a raised activated partial thromboplastin time (aPTT), and during the peripartum and postpartum period, concern for AHA should be raised as delays in diagnosis can be detrimental. Herein, we present a case of a 31-year-old female with sickle cell trait who developed venous bleeding and, later, neuraxial, musculoskeletal, and subcutaneous bleeding. She underwent an extensive course of treatment before getting into remission.

DOI

10.7759/cureus.16803

Volume

13

Issue

8

Publication Date

8-1-2021

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