Temporal, Spatial, and Epidemiologic Relationships of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Gene Cycle Thresholds: A Pragmatic Ambi-directional Observation

Authors

Emil Lesho, Rochester Regional HealthFollow
Lisa Reno, Rochester Regional HealthFollow
Donna Newhart, Rochester Regional HealthFollow
Robert Clifford, Bioinformatics, Cavia Partners, Silver Spring, Maryland, USA.
Olga Vasylyeva, Rochester Regional HealthFollow
John Hanna, Rochester Regional HealthFollow
Stephanie Yu, Rochester Regional HealthFollow
Jonathan Bress, Rochester Regional HealthFollow
Edward Walsh, Infectious Diseases Department, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA.Follow

Department

Infectious Diseases

Document Type

Article

Publication Title

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Abstract

Prospective serial sampling of 70 patients revealed clinically relevant cycle thresholds (Ct) occurring 9, 26, and 36 days after symptom onset. Race, gender, and corticosteroids apparently did not influence RNA positivity. In a retrospective analysis of 180 patients, initial Ct did not correlate with requirements for admission or intensive care.

DOI

10.1093/cid/ciaa1248

Publication Date

10-6-2020

Recommended Citation

Lesho, E., Reno, L., Newhart, D., Clifford, R., Vasylyeva, O., Hanna, J., Yu, S., Bress, J., & Walsh, E. (2020). Temporal, Spatial, and Epidemiologic Relationships of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Gene Cycle Thresholds: A Pragmatic Ambi-directional Observation. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America https://doi.org/10.1093/cid/ciaa1248