Chapter 65 - Venous thromboembolism in women: insights into epidemiology, risk factors, and clinical management

Editor

R. Troisi, K. Rexrode, Y. C. Cozier, & M. B. Goldman

Department

Internal Medicine

Document Type

Book Chapter

Publication Title

Women and Health

Abstract

Venous thromboembolism (VTE), which includes deep vein thrombosis and pulmonary embolism, is an important cause of morbidity and mortality, with sex-specific risk factors in female adults. Hormonal factors, including pregnancy, oral contraceptives, assisted reproductive technologies, and postmenopausal hormone therapy, are associated with increased thrombotic risk and present specific diagnostic and management challenges unique to women. This chapter adopts a sex-informed approach to examine the epidemiology, clinical presentation, diagnostic algorithms, imaging modalities, and treatment relevant to VTE in women. It also addresses contributions of genetic factors, social determinants of health, diagnostic bias, aging, and COVID-19-related coagulopathy to VTE risk in women.

First Page

1241

Last Page

1255

DOI

10.1016/B978-0-443-45863-7.00065-2

Publication Date

5-21-2026

Publisher

Academic Press

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