Chapter 18 - Regenerative medicine of the spine
Editor
R. T. Deer, & S. Diwan
Department
Neurosurgery
Document Type
Book Chapter
Publication Title
Minimally Invasive Spine Techniques: Modern Approaches
Abstract
Spinal structures, including discs, facets, and sacroiliac joints, are affected by deterioration from degeneration or trauma. Besides impairing function, facet and disc deterioration results in spinal stenosis and nerve root impingement. Its sequelae are chronic nociceptive and neuropathic pain. Regenerative applications attempt to reverse degenerative processes and/or support healing in defective tissues. Platelet-rich plasma, bone marrow aspirate concentrate, and adipose stem cells are emerging as agents facilitating these goals, either by reversing deterioration or by facilitating healing of injured tissues. In this chapter, we highlight the current evidence and utility of regenerative treatments for axial spine pain secondary to facet joint arthritis, degenerative disc disease, radicular pain, and sacroiliac joint-mediated pain.
First Page
225
Last Page
238
DOI
10.1016/B978-0-443-27568-5.00007-5
Publication Date
5-1-2026
Publisher
Academic Press
Recommended Citation
Abdullah, N., Latif, U., Gustafson, K., Vu, D. T., Evans, B., George, T. K., & Boev, A. (2026). Chapter 18 - Regenerative medicine of the spine. Minimally Invasive Spine Techniques: Modern Approaches, 225-238. https://doi.org/10.1016/B978-0-443-27568-5.00007-5