Updates in the Management of Peanut Allergy

Department

Allergy and Immunology

Document Type

Article

Publication Title

Annual Review of Medicine

Abstract

Peanut allergy is a significant rising public health problem affecting both children and adults. Early peanut introduction has been adopted in multiple westernized nations as a preventative strategic measure to reduce the risk of developing peanut allergy, although implementation faces barriers. Multiple therapies to treat peanut allergy have been developed, including oral immunotherapy and omalizumab as approved treatments to provide protection against reactions from accidental exposure and reduce the risk of anaphylaxis, offering options beyond strict avoidance. Strategies in the developmental pipeline include epicutaneous immunotherapy and sublingual immunotherapy. The future is bright for individuals with peanut allergy, as these breakthroughs can help address the fear, uncertainty, severity, and lack of protection that has become synonymous with this disease. Shared decision-making is needed to ensure that each patient receives the management approach best suited to their needs, preferences, and goals.

First Page

281

Last Page

295

DOI

10.1146/annurev-med-050224-121037

Volume

77

Issue

1

Publication Date

1-1-2026

Medical Subject Headings

Humans; Peanut Hypersensitivity; Desensitization, Immunologic; Omalizumab; Child; Anaphylaxis; Anti-Allergic Agents

PubMed ID

41592928

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