Anorectal Diseases in Rheumatology
Editor
Tadros, M., Shapiro, L., Frech, T., Wu, G.Y.
Department
Gastroenterology
Document Type
Book Chapter
Publication Title
GI Diseases Associated with Rheumatological and Vasculitic Conditions
Abstract
Although rare, anorectal involvement in rheumatic diseases (RD) can significantly impair quality of life. This chapter outlines normal anorectal anatomy and discusses how systemic sclerosis (SSc) causes sphincter dysfunction, neuropathy, and fecal incontinence through multiple mechanisms. Sarcoidosis, systemic lupus erythematosus (SLE), and antiphospholipid syndrome may present with anorectal plaques, ulcers, stenosis, or hemorrhoidal disease, often driven by granulomatous or vascular pathology. Treatment often focuses on sphincter muscle training in fecal incontinence form SSc and steroid therapy for SLE-related pathology, though further research is still needed. Recognizing anorectal symptoms may aid early diagnosis and facilitate coordinated care.
First Page
133
Last Page
141
DOI
10.1007/978-3-032-07868-1_9
Publication Date
1-1-2026
Publisher
Springer, Cham
Recommended Citation
Ashraf, M. F., Strader, M., Pearlstein, E., Ayer, D., & Batool, A. (2026). Anorectal Diseases in Rheumatology. GI Diseases Associated with Rheumatological and Vasculitic Conditions, 133-141. https://doi.org/10.1007/978-3-032-07868-1_9