Hepatosplenic T-Cell Lymphoma in an Immunocompetent Young Male: A Challenging Diagnosis

Authors

Mohammad Ammad Ud Din, Rochester Regional HealthFollow
Ronald Sham, Rochester Regional HealthFollow
Syed Ather Hussain, Rochester Regional HealthFollow
Joel Shapiro, Rochester Regional HealthFollow

Department

Internal Medicine

Document Type

Article

Publication Title

Cureus

Abstract

Hepatosplenic T-cell lymphoma is a rare but highly aggressive form of T-cell malignancy. As cases are not routinely seen in practice, the malignancy can be confused with other hematologic conditions that have a similar presentation. Here in, we present the challenges faced in diagnosing a 27-year-old-male who initially presented with asymptomatic pancytopenia and then developed massive splenomegaly over the next three months. After an elaborate workup, including a bone marrow biopsy and extensive serological testing, which all turned out to be negative, he eventually underwent a splenectomy with biopsy results confirming hepatosplenic T-cell lymphoma.

First Page

e8993

DOI

10.7759/cureus.8993

Volume

12

Issue

7

Publication Date

8-11-2020

Recommended Citation

Ammad Ud Din, M., Sham, R., Hussain, S. A., & Shapiro, J. (2020). Hepatosplenic T-Cell Lymphoma in an Immunocompetent Young Male: A Challenging Diagnosis. Cureus, 12 (7), e8993. https://doi.org/10.7759/cureus.8993