Hepatosplenic T-Cell Lymphoma in an Immunocompetent Young Male: A Challenging Diagnosis
Hepatosplenic T-cell lymphoma is a rare but highly aggressive form of T-cell malignancy. As cases are not routinely seen in practice, the malignancy can be confused with other hematologic conditions that have a similar presentation. Here in, we present the challenges faced in diagnosing a 27-year-old-male who initially presented with asymptomatic pancytopenia and then developed massive splenomegaly over the next three months. After an elaborate workup, including a bone marrow biopsy and extensive serological testing, which all turned out to be negative, he eventually underwent a splenectomy with biopsy results confirming hepatosplenic T-cell lymphoma.
Ammad Ud Din, Mohammad; Sham, Ronald; Hussain, Syed Ather; and Shapiro, Joel, "Hepatosplenic T-Cell Lymphoma in an Immunocompetent Young Male: A Challenging Diagnosis" (2020). Rochester Regional Health authored publications and proceedings. 315.