Infant anaphylaxis and epinephrine use: Can we improve acute management?

Department

Allergy and Immunology

Document Type

Article

Publication Title

Journal of Food Allergy

Abstract

BACKGROUND: Anaphylaxis is a serious systemic hypersensitivity reaction that is rapid in onset and may cause death.

METHODS: The true prevalence of infant anaphylaxis is unknown, but such cases may be increasing in presentation of these patients to emergency departments, with studies that evaluate health-care utilization after implementation of early introduction guidelines that report an increase in the use of emergency department for food-related visits as well as an increase in epinephrine prescriptions for infants.

RESULTS: Reasons for these increases may include early food introduction as well as therapeutic interventions such as early life or preschool oral immunotherapy.

CONCLUSION: Infant anaphylaxis presents many diagnostic challenges, including poor recognition attributable to confusing signs and symptoms that may be age specific, and risk for inadequate acute management.

First Page

39

Last Page

41

DOI

10.2500/jfa.2025.7.240067

Volume

7

Issue

1

Publication Date

8-1-2024

PubMed ID

40771706

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