Temporal trends and procedural safety of mitral valve transcatheter edge to edge repair in patients with previous CABG

Authors

Asmaa Ahmed, Rochester Regional HealthFollow
Mahmoud Eisa, Rochester Regional HealthFollow
Andrew Takla, Rochester Regional HealthFollow
Sahej Manesh Singh Arora, Rochester Regional HealthFollow
Mohamed Salah Mohamed, Rochester Regional HealthFollow
Amir Hanafi, Rochester Regional HealthFollow
Scott Feitell, Rochester Regional HealthFollow

Department

Internal Medicine

Additional Department

Cardiology

Document Type

Article

Publication Title

Future Cardiology

Abstract

Introduction: Mitral Valve Transcatheter Edge-to-Edge Repair (M-TEER) is a minimally invasive procedure for patients with symptomatic mitral regurgitation. Its outcomes in patients with a history of coronary artery bypass grafting (CABG) remain unclear.

Methodology: We analyzed data from the Nationwide Inpatient Sample, using ICD-10-CM codes for M-TEER and CABG. Primary outcomes included in-hospital all-cause mortality and periprocedural cardiac complications. Inverse probability of treatment weighting was employed to compare M-TEER patients with or without prior CABG.

Results: From January 2016 to December 2020, we identified 48,835 M-TEER cases in the U.S. with 9,655 patients (19.78%) having a prior CABG. These patients were older and had more comorbidities. M-TEER procedures increased over the study period, including those with prior CABG (2,145 in 2016 vs. 2,682 in 2020). Adjusted analysis showed no significant difference in in-hospital mortality between patients with and without prior CABG [adjusted odds ratio (aOR) 0.85, 95% confidence interval (CI) 0.85-1.32, p = 0.47]. However, patients with prior CABG had lower odds of periprocedural cardiac complications [aOR 0.72, 95% CI 0.59-0.87, p = 0.001].

Conclusions: M-TEER appears safe for patients with prior CABG, showing no adverse peri-procedural outcomes compared to those without CABG. Despite more comorbidities, M-TEER remains a safe option for these patients.

First Page

15

Last Page

22

DOI

10.1080/14796678.2024.2442238

Volume

21

Issue

1

Publication Date

1-1-2025

Medical Subject Headings

Humans; Female; Male; Mitral Valve Insufficiency; Coronary Artery Bypass; Aged; Cardiac Catheterization; Hospital Mortality; United States; Middle Aged; Postoperative Complications; Mitral Valve; Retrospective Studies; Heart Valve Prosthesis Implantation; Treatment Outcome; Aged, 80 and over

PubMed ID

39716767

Recommended Citation

Ahmed, A., Eisa, M., Takla, A., Arora, S., Mohamed, M. S., Hanafi, A., & Feitell, S. (2025). Temporal trends and procedural safety of mitral valve transcatheter edge to edge repair in patients with previous CABG. Future Cardiology, 21 (1), 15-22. https://doi.org/10.1080/14796678.2024.2442238