Unveiling the Hazards: A Case Report on Kayexalate-induced Colonic Necrosis

Department

Internal Medicine

Additional Department

Gastroenterology

Document Type

Article

Publication Title

Journal of Community Hospital Internal Medicine Perspectives

Abstract

Sodium polystyrene sulphonate (SPS), employed in the management of severe hyperkalemia, is typically combined with sodium sorbitol to avert potential intestinal obstruction. Nonetheless, the administration of Kayexalate, even in the presence of minimal sorbitol, can lead to the grave complication of colonic necrosis. We present a case of Kayexalate-mediated colonic necrosis, highlighting the vital necessity of acknowledging the inherent risks associated with its usage in spite of its efficacy in potassium reduction. In light of these potential risks, it is incumbent upon physicians to exercise caution, and contemplate the use of alternative pharmacological agents that effectively eliminate excess potassium, whilst minimizing associated adverse effects.

First Page

54

Last Page

57

DOI

10.55729/2000-9666.1264

Volume

13

Issue

6

Publication Date

11-1-2023

PubMed ID

38596555

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