Angioinvasive gastrointestinal mucormycosis with duodenal necrosis and perforation in a patient with visceral myopathy

Department

Internal Medicine

Additional Department

Pathology

Document Type

Article

Publication Title

Zeitschrift fur Gastroenterologie

Abstract

A 55-year-old woman with a past medical history of visceral myopathy with multiple resultant abdominal surgeries, colectomy caused by severe pseudo-obstruction, and end-stage renal disease on hemodialysis presented with complaints of nausea, abdominal distention, vomiting, and diarrhea for five days. Small-bowel obstruction was identified on CT. She subsequently developed acute gastrointestinal bleeding, anemia, and hemodynamic instability. Extensive gastric ulceration with frank hemorrhage prompted urgent subtotal gastrectomy with multiple intraoperative findings, including a necrotic distal duodenum. Surgical pathology showed invasive fungal infection of the duodenum with perforation, morphologically compatible with invasive mucormycosis. The patient was started on intravenous liposomal amphotericin B, but despite best efforts, the patient ultimately succumbed to this invasive fungal infection in addition to sepsis and multi-organ failure.

First Page

199

Last Page

203

DOI

10.1055/a-2053-9149

Volume

62

Issue

2

Publication Date

2-1-2024

Medical Subject Headings

Female; Humans; Middle Aged; Mucormycosis (complications, diagnosis, surgery); Duodenum; Intestinal Pseudo-Obstruction; Necrosis (diagnosis); Invasive Fungal Infections

PubMed ID

37044123

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