Toxic Megacolon leading to bowel perforation: A rare adverse effect of bortezomib
Department
Internal Medicine
Document Type
Article
Publication Title
Journal of Clinical Images and Medical Case Reports
Abstract
Bortezomib is a chemotherapeutic drug used in the treatment of multiple myeloma and amyloidosis. The major dose-limiting adverse effect is neuropathy. Although rare, autonomic involvement of the gastrointestinal tract, can present with ileus. We report a compelling case highlighting the association between Bortezomib initiation and development of life-threatening toxic megacolon.
DOI
10.52768/2766-7820/2333
Volume
4
Publication Date
3-2023
Recommended Citation
Gill, P., Bhalla, V., Mulkareddy, V., & Sitaraman, K. (2023). Toxic Megacolon leading to bowel perforation: A rare adverse effect of bortezomib. Journal of Clinical Images and Medical Case Reports, 4 https://doi.org/10.52768/2766-7820/2333
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