Variations in Penile Cancer Management: Results From the Global Society of Rare Genitourinary Tumors Survey
Department
Urology
Document Type
Article
Publication Title
Clinical Genitourinary Cancer
Abstract
Introduction: There is paucity of evidence and consensus on various aspects of management of penile cancer (PeCa), which is intuitive considering the rarity of this disease. We present here the details of an online survey conducted by the Global Society of Rare Genito-urinary Tumors (GSRGT) with the aim of capturing the variations in PeCa care across different regions of the world.
Materials and methods: An online questionnaire was developed by experts within the GSRGT and then circulated via email in English and Spanish versions to clinicians dealing with PeCa. Respondents were allowed 8 weeks to reply.
Results: We received 102 responses; the majority of them were from South America (37.2%) followed by North America and Asia (17.6% each). Only 11.7% of the respondents treated more than 25 patients with PeCa annually. Total penectomy is performed by 21.5% of the respondents in > 50% of their patients. Less than a fifth of the experts (19.6%) responded that > 50% of their patients are clinically node-negative (cN0) at presentation. For intermediate-risk cN0 patients (T1 G2 cancer), about a third of the experts chose surveillance. For invasive inguinal staging, the options of Dynamic Sentinel Lymph Node Biopsy (DSNB), Modified Inguinal Lymph Node Dissection (MILD), Superficial Inguinal Lymph Node Dissection (SILD), and Video-Endoscopic Inguinal Lymphadenectomy (VEIL) were chosen by 28.4%, 26.4%, 31.3%, and 13.7% of the respondents respectively. Considerable variation was seen in the worldwide use of these techniques. For clinically node-positive patients, respondents were in favor of giving adjuvant chemotherapy instead of neoadjuvant chemotherapy, except for cN3 patients.
Conclusion: The results of this questionnaire objectified the variations in global practices in the management of PeCa. This serves as the baseline information which can help prioritize research areas for multinational collaborative efforts, a key mission of the GSRGT.
First Page
376
Last Page
382
DOI
10.1016/j.clgc.2023.03.001
Volume
21
Issue
3
Publication Date
6-1-2023
Medical Subject Headings
Male; Humans; Penile Neoplasms (pathology); Sentinel Lymph Node Biopsy (methods); Lymph Node Excision (methods); Lymph Nodes (pathology); Penis (pathology); Neoplasm Staging
PubMed ID
37037737
Recommended Citation
Prakash, G., Arora, A., Bandini, M., Basile, G., Pal, M., Griffiths, G., Cornes, R., Zhu, Y., Rodriguez, A., Alberson, M., Necchi, A., Master, V., Pettaway, C. A., & Spiess, P. E. (2023). Variations in Penile Cancer Management: Results From the Global Society of Rare Genitourinary Tumors Survey. Clinical Genitourinary Cancer, 21 (3), 376-382. https://doi.org/10.1016/j.clgc.2023.03.001