A Case of a Beta-Catenin-Activated Hepatic Adenoma in a Male Patient With Familial Adenomatous Polyposis
Department
Internal Medicine
Document Type
Article
Publication Title
ACG Case Reports Journal
Abstract
Hepatocellular adenoma is a benign liver tumor often diagnosed incidentally in women of reproductive age who are taking oral contraceptives. In this study, we present a unique case of an 18-year-old man with known familial adenomatous polyposis who presented with sepsis in the setting of a recent total proctocolectomy and was incidentally found to have multiple large hepatic lesions. A biopsy of a liver lesion confirmed the diagnosis of a beta-catenin-activated hepatic adenoma. To the best of our knowledge, this is the first known case of beta-catenin-activated hepatic adenoma in a patient with a known familial adenomatous polyposis mutation. Beta-catenin is one of the many subtypes of hepatocellular adenomas, which carries a high risk of malignant transformation.
First Page
e01012
DOI
10.14309/crj.0000000000001012
Volume
10
Issue
3
Publication Date
3-1-2023
PubMed ID
36936132
Recommended Citation
Kusnik, A., Li, S., Graziano, E., Katerji, R., & Ramaraju, G. (2023). A Case of a Beta-Catenin-Activated Hepatic Adenoma in a Male Patient With Familial Adenomatous Polyposis. ACG Case Reports Journal, 10 (3), e01012. https://doi.org/10.14309/crj.0000000000001012