Can Analysis of Routine Viral Testing Provide Accurate Estimates of Respiratory Syncytial Virus Disease Burden in Adults?
Department
Medicine
Document Type
Article
Publication Title
The Journal of Infectious Diseases
Abstract
Respiratory syncytial virus (RSV) is increasingly recognized as a significant cause of adult respiratory illness. We evaluated routine viral testing and discharge diagnoses for identifying RSV and influenza burden. Polymerase chain reaction results performed in adults during emergency room visits or hospitalizations were reviewed. Peak RSV activity preceded influenza activity by 8 weeks. The ratio of total number of viral tests performed divided by total number of respiratory visits was higher during influenza than RSV peaks (1.31 vs 0.72; P = .0001). Influenza and RSV were listed primary diagnoses in 56 (30%) vs 7 (6%), respectively (P < .0001). Routine viral testing to estimate adult RSV disease burden has limitations.
First Page
1706
Last Page
1710
DOI
10.1093/infdis/jix196
Volume
215
Issue
11
Publication Date
6-1-2017
Medical Subject Headings
Adult; Diagnostic Tests, Routine (statistics & numerical data); Humans; Influenza, Human; Polymerase Chain Reaction; Respiratory Syncytial Virus Infections (diagnosis, epidemiology, virology); Respiratory Syncytial Virus, Human; Retrospective Studies; Virology (statistics & numerical data)
PubMed ID
28863444
Recommended Citation
Datta, S., Walsh, E. E., Peterson, D. R., & Falsey, A. R. (2017). Can Analysis of Routine Viral Testing Provide Accurate Estimates of Respiratory Syncytial Virus Disease Burden in Adults?. The Journal of Infectious Diseases, 215 (11), 1706-1710. https://doi.org/10.1093/infdis/jix196