Delayed Recognition of Levetiracetam-induced Pancytopenia

Department

Internal Medicine

Document Type

Article

Publication Title

European Journal of Case Reports in Internal Medicine

Abstract

Blood dyscrasias associated with levetiracetam use can be difficult to identify, especially when other potential differential diagnoses are concurrently present. Here we present a 57-year-old man with metastatic adenocarcinoma of unknown primary origin on levetiracetam who initially presented with an in-stent thrombosis of the right external iliac vein and then developed worsening thrombocytopenia followed by pancytopenia. Levetiracetam was not identified as the culprit until other causes like platelet consumption, heparin-induced thrombocytopenia, idiopathic immune thrombocytopenic purpura, and bone marrow involvement by metastatic disease were ruled out.

First Page

002449

DOI

10.12890/2021_002449

Volume

8

Issue

3

Publication Date

3-30-2021

PubMed ID

33869106

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