Flexible quantum dot light-emitting devices for targeted photomedical applications

Hao Chen, College of Optics and Photonics, University of Central Florida, Orlando, FL, USA. Nanoscience Technology Center, University of Central Florida, Orlando, FL, USA.
Tzu-Hung Yeh, Department of Electronic Engineering, National Taiwan University of Science and Technology, Taipei City, Taiwan. Organic Electronics Research Center, Ming Chi University of Technology, New Taipei City, Taiwan.
Juan He, College of Optics and Photonics, University of Central Florida, Orlando, FL, USA.
Caicai Zhang, Nanoscience Technology Center, University of Central Florida, Orlando, FL, USA. Department of Materials Science & Engineering, University of Central Florida, Orlando, FL, USA.
Robert Abbel, Holst Centre-TNO, Eindhoven, Netherlands.
Michael R. Hamblin, Harvard Medical School, Wellman Center for Photomedicine, Boston, MA, USA.
Yingying Huang, Harvard Medical School, Wellman Center for Photomedicine, Boston, MA, USA.
Raymond J. Lanzafame, Rochester Regional Health
Istvan Stadler, Rochester Regional HealthFollow
Jonathan Celli, Department of Physics, University of Massachusetts Boston, Boston, MA, USA.
Shun-Wei Liu, Organic Electronics Research Center, Ming Chi University of Technology, New Taipei City, Taiwan.
Shin-Tson Wu, College of Optics and Photonics, University of Central Florida, Orlando, FL, USA.
Yajie Dong, College of Optics and Photonics, University of Central Florida, Orlando, FL, USA. Nanoscience Technology Center, University of Central Florida, Orlando, FL, USA. Department of Materials Science & Engineering, University of Central Florida, Orlando, FL, USA.

Department

Surgery

Document Type

Article

Publication Title

Journal Of The Society For Information Display

Abstract

Quantum dot light-emitting devices (QLEDs), originally developed for displays, were recently demonstrated to be promising light sources for various photomedical applications, including photodynamic therapy cancer cell treatment and photobimodulation cell metabolism enhancement. With exceptional emission wavelength tunability and potential flexibility, QLEDs could enable wearable, targeted photomedicine with maximized absorption of different medical photosensitizers. In this paper, we report, for the first time, the in vitro study to demonstrate that QLEDs-based photodynamic therapy can effectively kill Methicillin-resistant , an antibiotic-resistant bacterium. We then present successful synthesis of highly efficient quantum dots with narrow spectra and specific peak wavelengths to match the absorption peaks of different photosensitizers for targeted photomedicine. Flexible QLEDs with a peak external quantum efficiency of 8.2% and a luminance of over 20,000 cd/m at a low driving voltage of 6 V were achieved. The tunable, flexible QLEDs could be employed for oral cancer treatment or diabetic wound repairs in the near future. These results represent one fresh stride toward realizing QLEDs' long-term goal to enable the wide clinical adoption of photomedicine.

First Page

296

Last Page

303

DOI

10.1002/jsid.650

Volume

26

Issue

5

Publication Date

5-1-2018

PubMed ID

30416331

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