Food Protein-Induced Enterocolitis Syndrome

Authors

Theresa A. Bingemann, Rochester Regional HealthFollow
Puja Sood, Division of Pediatric Allergy and Immunology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA.
Kirsi M. Järvinen, Division of Pediatric Allergy and Immunology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA.

Department

Allergy and Immunology

Document Type

Article

Publication Title

Immunology And Allergy Clinics Of North America

Abstract

Food protein-induced enterocolitis syndrome (FPIES) is a non-IgE-mediated food allergy that usually presents in infancy. Cow's milk, soy, and grains are the most common food triggers. FPIES can present as a medical emergency with symptoms including delayed persistent emesis or diarrhea that can lead to severe dehydration and hemodynamic instability with abnormal laboratory markers. Diagnosis can often be made based on clinical history and noted improvement in symptoms once the suspected triggers have been removed from the diet, with oral food challenge as the gold standard for confirmation of diagnosis in unclear cases.

First Page

141

Last Page

152

DOI

10.1016/j.iac.2017.09.009

Volume

38

Issue

1

Publication Date

2-1-2018

Medical Subject Headings

Allergens (immunology); Animals; Diarrhea; Edible Grain (immunology); Enterocolitis (diagnosis); Failure to Thrive; Food; Food Hypersensitivity (diagnosis); Humans; Immunization; Infant; Milk Proteins (immunology); Soybean Proteins (immunology); Syndrome; Vomiting

PubMed ID

29132670

Recommended Citation

Bingemann, T. A., Sood, P., & Järvinen, K. M. (2018). Food Protein-Induced Enterocolitis Syndrome. Immunology And Allergy Clinics Of North America, 38 (1), 141-152. https://doi.org/10.1016/j.iac.2017.09.009