Kounis syndrome – Anaphylaxis-induced acute coronary syndrome

Authors

Austin T. Thacker DO, Rochester Regional Health SystemFollow
Brachman Herzig OMS, Lake Erie College of Osteopathic Medicine -Erie Campus,Follow
Brendan Robinson DO, United Memorial Medical Center -Rochester Regional Health.Follow
Ahad Anjum DO, Rochester Regional Health SystemFollow

Author Credentials

Austin Thacker, DO PGY-2

Brachman Herzig, OMS-III

Brendan Robinson, DO

Ahad Anjum, DO

Abstract

Kounis syndrome is an underdiagnosed condition in which anaphylaxis triggers vasospastic acute coronary syndrome, either with or without underlying coronary artery disease. The prevalence of this syndrome among hospitalized patients for allergic/hypersensitivity/anaphylactic reactions in the United States is 1.1%, with a 7% rate of all-cause inpatient mortality. This article presents an anaphylaxis-induced acute coronary syndrome case in a patient with underlying coronary artery disease. The pathophysiological mechanism of anaphylactic-induced acute coronary syndrome involves the inflammatory mediators of type I hypersensitivity reactions.

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License

Recommended Citation

Thacker AT, Herzig B, Robinson B, Anjum A. Kounis syndrome – Anaphylaxis-induced acute coronary syndrome. Advances in Clinical Medical Research and Healthcare Delivery. 2023; 3(4). doi: 10.53785/2769-2779.1178.

Publisher Note

All articles published in ACMRHD are distributed with a Creative Commons CC BY-NC 4.0 license. Under this license, authors hold the copyright to their work and have the right to share or adapt the article with no restrictions, as long as the author(s) and source are cited, and the use is for noncommercial purposes. This policy went into effect November 1, 2023, and applies retroactively to all articles published in ACMRHD prior to that date, as well.