Epidermoid cysts are the most common cutaneous cysts, and infrequently develop within mucosal or glandular tissue. Rarely, epidermoid cysts have been described as arising within the thyroid gland in the form of a nodule. In this paper, we describe a case of a 72-year-old female with a suspicious-appearing thyroid nodule on ultrasound, which was eventually found to be an epidermoid cyst. To our knowledge, this is the first surgical biopsy-proven case that demonstrates an intrathyroid epidermoid cyst in multiple radiographic modalities including ultrasound, nuclear medicine I-123 thyroid scan, and MRI. In addition, we present a concise review of previously described cases of intrathyroid epidermoid cysts, including patient clinical manifestations, initial sonographic appearance, and management of lesions. This case reinforces the importance of considering rare diagnoses in the workup of a thyroid nodule based on its sonographic appearance.
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Hadigal SR, Frate B, Lone S, Salamone F, Sachica C, Pyne R. A case report and literature review of an intrathyroid epidermoid cyst. Advances in Clinical Medical Research and Healthcare Delivery. 2022; 2(2). doi: 10.53785/2769-2779.1092.