Article Title

Risk of Venous Thromboembolism: The Prothrombin-G20210A Mutation and Combined Oral Contraceptives

Authors

Nedal Darwish MD, Arnot Ogden Medical CenterFollow
Halima Bakillah MD, Arnot Ogden Medical CenterFollow
Ganesh Arun DO, Arnot Ogden Medical CenterFollow
Sowmya Srinivas MD, Arnot Ogden Medical CenterFollow
Mohamed Manaa MD, Arnot Ogden Medical CenterFollow
Kyle Berliner, Arnot Ogden Medical CenterFollow
Dayakar Reddy MD, Arnot Ogden Medical CenterFollow

Author Credentials

Halima Bakillah MD

Nedal Darwish MD

Ganesh Arun DO

Sowmya Srinivas MD

Mohamed Manaa MD

Dayakar Reddy MD

Author ORCID Identifier

0000-0003-2776-3748

Abstract

The risk of venous thromboembolism in oral contraceptive pill users becomes dramatically increased in patients with inherited thrombophilias. The often undiscovered prothrombotic genetic conditions pose a potentially deadly threat to its generally young demographic. When thrombosis is discovered in oral contraceptive pill users with a strong family history of related events, it becomes essential to screen for prothrombotic genetic conditions and further mitigate any associated modifiable risk factors. Here we present a case of pulmonary embolism requiring cardiopulmonary resuscitation in 30-year-old female found to have a Prothrombin G20210A on oral contraceptive pills. The emergent management of the critical case, as well as the subsequent evaluation for prothrombotic conditions and the role of potential screening is discussed.

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License

Recommended Citation

Darwish N, Bakillah H, Arun G, Srinivas S, Manaa M, Berliner K, Reddy D. Risk of Venous Thromboembolism: The Prothrombin-G20210A Mutation and Combined Oral Contraceptives. Advances in Clinical Medical Research and Healthcare Delivery. 2022; 2(2). doi: 10.53785/2769-2779.1097.