The Diagnostic Dilemma of Sarcoidosis: A Case of Acute Hypercalcemia

Authors

Vani Mulkareddy, Rochester Regional HealthFollow
Varun Bhalla, Rochester Regional HealthFollow
Soham Upadhye, Rochester Regional HealthFollow
Preeti Siddam, Rochester Regional HealthFollow

Department

Internal Medicine

Document Type

Article

Publication Title

Cureus

Abstract

Hypercalcemia is a common clinical laboratory abnormality with a majority of cases attributed to malignancy or hyperparathyroidism. Although hypercalcemia is a common manifestation of sarcoidosis, it is rarely the initial presentation. Here we present a case of acute hypercalcemia in a 60-year-old gentleman, which was diagnosed as sarcoidosis following an elaborate workup, including radiological assessment and multiple organ biopsies. This case highlights the diagnostic dilemma of sarcoidosis due to varying clinical presentation that can mimic multiple conditions, including malignancy. Biopsy showing noncaseating granulomas is pathognomic of sarcoidosis. Due to its multisystemic and nonspecific presentation, selecting an appropriate biopsy site is key to diagnosis.

First Page

e10399

DOI

10.7759/cureus.10399

Volume

12

Issue

9

Publication Date

10-17-2020

Recommended Citation

Mulkareddy, V., Bhalla, V., Upadhye, S., & Siddam, P. (2020). The Diagnostic Dilemma of Sarcoidosis: A Case of Acute Hypercalcemia. Cureus, 12 (9), e10399. https://doi.org/10.7759/cureus.10399