Ablation of the Gastric Cardia for GERD: A Comprehensive Technical and Clinical Review
Department
Internal Medicine
Document Type
Article
Publication Title
Practical Gastroenterology
Abstract
Anti-Reflux Mucosal Ablation (ARMA) is an innovative endoscopic intervention for managing PPI-refractory GERD by enhancing the structural integrity of the gastroesophageal junction (GEJ). Utilizing controlled thermal ablation, ARMA induces localized mucosal fibrosis to reinforce the anti-reflux barrier. Clinical studies demonstrate significant improvements in GERD symptoms, acid exposure time, and DeMeester scores, with over 70% clinical success in one year. The procedure is well-tolerated, with manageable complications such as transient stenosis treated via endoscopic dilation. ARMA offers advantages over surgical fundoplication due to its reduced procedural complexity and minimally invasive nature. While early outcomes are promising, larger multicenter trials are needed to validate long-term efficacy and define optimal patient selection, particularly in those with mild to moderate GEJ abnormalities.
First Page
18
Last Page
23
Volume
49
Issue
5
Publication Date
5-1-2025
Recommended Citation
Malik, S., & Adler, D. G. (2025). Ablation of the Gastric Cardia for GERD: A Comprehensive Technical and Clinical Review. Practical Gastroenterology, 49 (5), 18-23. Retrieved from https://scholar.rochesterregional.org/rrhpubs/2862