Wiskott-Aldrich Syndrome

Authors

Muhammad Ahmed Malik, Rochester Regional HealthFollow
Muhammad Masab

Department

Internal Medicine

Document Type

Book Chapter

Publication Title

StatPearls [Internet]

Abstract

Wiskott-Aldrich syndrome is a rare X-linked disorder with a characteristic triad of immunodeficiency, thrombocytopenia, and eczema. It results from a genetic mutation in the gene encoding Wiskott-Aldrich syndrome protein (WASp) affecting the immune system and inducing a state of immunodeficiency. The disease follows a broad spectrum depending on gene mutations ranging from severe phenotype (classic WAS) to milder ones (X-linked thrombocytopenia (XLT) and X-linked neutropenia).

Publication Date

6-26-2023

Publisher

StatPearls Publishing

PubMed ID

30969660

Recommended Citation

Malik, M. A., & Masab, M. (2023). Wiskott-Aldrich Syndrome. StatPearls [Internet] Retrieved from https://scholar.rochesterregional.org/rrhpubs/2130