Scholarly publications and presentations by Rochester Regional Health's Research department authors.
Submissions from 2023
Acute otitis media pneumococcal disease burden and nasopharyngeal colonization in children due to serotypes included and not included in current and new pneumococcal conjugate vaccines, Michael Pichichero, Richard Malley, Ravinder Kaur, Robert Zagursky, and Porter Anderson
Vaccine target and carrier molecule nontypeable Haemophilus influenzae protein D dimerizes like the close Escherichia coli GlpQ homolog but unlike other known homolog dimers, Seth P. Jones, Kali H. Cook, Melody L. Holmquist, Liam J. Almekinder, Annie M. Delaney, Ryhl Charles, Natalie Labbe, Janai Perdue, Niaya Jackson, Michael E. Pichichero, Ravinder Kaur, Lea V. Michel, and Michael L. Gleghorn
Window of Susceptibility to Acute Otitis Media Infection, Peter Bajorski, Naoko Fuji, Ravinder Kaur, and Michael E. Pichichero
Submissions from 2022
Antibiotic Use and Vaccine Antibody Levels, Timothy J. Chapman, Minh Pham, Peter Bajorski, and Michael E. Pichichero
Computational prediction of intracellular targets of wild-type or mutant vesicular stomatitis matrix protein, Matthew C. Morris, Thomas M. Russell, Cole A. Lyman, Wesley K. Wong, Gordon Broderick, and Maureen C. Ferran
Haemophilus influenzae Protein D antibody suppression in a multi-component vaccine formulation, Lea V. Michel, Ravinder Kaur, Michael L. Gleghorn, Melody Holmquist, Karin Pryharski, Janai Perdue, Seth P. Jones, Niaya Jackson, Isabelle Pilo, Anna Kasper, Natalie Labbe, and Michael Pichichero
Harnessing the Proteome in COPD to Identify Individuals Vulnerable to Frequent Exacerbations, S Sethi, Matthew Morris, Spencer Richman, X Zhu, S Shen, S Qian, M J. Mammen, J Qu, and Gordon Broderick
High Fidelity Modeling of Pulse Dynamics Using Logic Networks, Cole A. Lyman, Matthew M. Morris, Spencer Richman, and Gordon Broderick
Identification of Novel Biomarkers for COPD Phenotypes by Large-Scale Proteomics Analysis with UHR-IonStar, S Sethi, X Zhu, S Shen, S Qian, Gordon Broderick, Matthew Morris, Manoj J. Mammen, and J Qu
Interferon-γ promotes monocyte-mediated lung injury during influenza infection, Taylor Schmit, Kai Guo, and Michael E. Pichichero
Leveraging Drug-Target Interaction Data for the Translation of Computational Models into Clinically Actionable Interventions, Spencer C. Richman, Cole A. Lyman, Matthew C. Morris, and Gordon Broderick
Lipidation of Haemophilus influenzae Antigens P6 and OMP26 Improves Immunogenicity and Protection against Nasopharyngeal Colonization and Ear Infection, Ravinder Kaur and Michael E. Pichichero
Mapping the network biology of metabolic response to stress in posttraumatic stress disorder and obesity, Thomas P. Chacko, J Tory Toole, Spencer Richman, Garry L. Spink, Matthew J. Reinhard, Ryan C. Brewster, Michelle E. Costanzo, and Gordon Broderick
Network Modeling of Complex Time-Dependent Changes in Patient Adherence to Adjuvant Endocrine Treatment in ER+ Breast Cancer, Eileen H. Shinn, Brooke E. Busch, Neda Jasemi, Cole A. Lyman, J Tory Toole, Spencer C. Richman, William Fraser Symmans, Mariana Chavez-MacGregor, Susan K. Peterson, and Gordon Broderick
Old drugs, new tricks: leveraging known compounds to disrupt coronavirus-induced cytokine storm, Spencer Richman, Cole Lyman, Anastasia Nesterova, Anton Yuryev, Matthew Morris, Hongbao Cao, Chris Cheadle, Gary Skuse, and Gordon Broderick
Pathogenesis of Streptococcus pneumoniae serotype 3 during natural colonization and infections among children and its IgG correlate of protection in a mouse model, Naoko Fuji, Michael Pichichero, and Ravinder Kaur
Probing the potential interactions between two protein vaccine candidates from Nontypeable Haemophilus influenzae, Grace McGinnity, Janai Perdue, Natalie Labbe, Ravinder Kaur, Melody Holmquist, and Lea Michel
Proteomic Network Analysis of Bronchoalveolar Lavage Fluid in Ex-Smokers to Discover Implicated Protein Targets and Novel Drug Treatments for Chronic Obstructive Pulmonary Disease, Manoj J. Mammen, Chengjian Tu, Matthew C. Morris, Spencer Richman, William Mangione, Zackary Falls, Jun Qu, Gordon Broderick, Sanjay Sethi, and Ram Samudrala
Randomized Mechlorethamine/Chlormethine Induced Dermatitis Assessment Study (MIDAS) Establishes Benefit of Topical Triamcinolone 0.1% Ointment Cotreatment in Mycosis Fungoides, Carolina V. Alexander-Savino, Catherine G. Chung, Elaine S. Gilmore, Sean M. Carroll, and Brian Poligone
Refinement of Biological Regulatory Graphs using Functional Enrichment, Jeffrey M. Page, Matthew C. Morris, Gary Skuse, and Gordon Broderick
Submissions from 2021
Attractor Landscapes as a Model Selection Criterion in Data Poor Environments, Cole A. Lyman, Spencer Richman, Matthew C. Morris, and Gordon Broderick
A Vaccine Candidate Case Study: Understanding Protein D Antibody Suppression by Omp26, Anna Kasper, Niaya Jackson, and Ravinder Kaur
Can Machine Learning and AI Replace Otoscopy for Diagnosis of Otitis Media?, Michael E. Pichichero
Comparison of Specific In-vitro Virulence Gene Expression and Innate Host Response in Locally Invasive vs Colonizer Strains of Streptococcus Pneumoniae, Naoko Fuji, Michael E. Pichichero, and Ravinder Kaur
Gulf War Illness Clinical Trials and Interventions Consortium (GWICTIC): A Collaborative Research Infrastructure for Intervention and Implementation, Amanpreet K. Cheema, Rebecca B. McNeil, Travis Craddock, Gordon Broderick, Maria M. Abreu, Kristina Aenlle, Drew A. Helmer, J Wesson Ashford, Kimberly Sullivan, Alison Bested, Devra E. Cohen, Dikoma Shungu, Helena Chandler, Mary Ann Fletcher, Maxine Krengel, and Nancy Klimas
